Effect of Aqueous Mahogany (Khaya Senegalensis) Bark Extract on Haematology and Serum Biochemistry of Broiler Chickens in a Semi-Arid area of Nigeria
Abstract
Abstract
A total of two hundred (200) day-old Arbor Acre broiler chicks (mixed-sex) were used to study the effects of mahogany (Khaya senegalensis) bark aqueous extract on the haematology and serum biochemistry of broiler chickens in a semi-arid area of Nigeria. The chicks were weighed and allotted to five (5) treatments of aqueous mahogany bark extract (AMBE) in groups of forty (40) and replicated four times in groups of ten (10) chicks per replicate in a completely randomized design (CRD). Treatment 1 was the control having 0.00 ml/l of AMBE while treatments 2, 3, 4 and 5 were given 12.50, 25.00, 37.50 and 50.00 ml per litre of aqueous mahogany bark extract. The experiment lasted for a period of eight (8) weeks (56 days). Data on haematology and serum biochemical indices were collected and analyzed. The results on haematological indices showed significant (P<0.05) differences for packed cell volume (PCV), haemoglobin (Hb), red blood cells (RBC), white blood cells (WBC), mean corpuscular volume (MCV), mean corpuscular haemoglobin (MCH), mean corpuscular haemoglobin concentration (MCHC) and differential counts. However, PCV values (24.50 – 26.75 %) were slightly below the normal range (27 – 33 %) while MCV and MCH had values lower than the normal range. Significant (P<0.05) differences were also recorded for total protein, albumin, globulin, aspartate aminotransferase (ASAT), alanine aminotransferase (ALAT), alkaline phosphate (ALP), glucose, cholesterol, urea, creatinine, chloride, potassium, bicarbonate, sodium, direct bilirubin and conjugated bilirubin. Highest (P<0.05) total protein (72.75 g/L) was record in T4 (37.50 ml/L), T5 (50.00 ml/L) had the highest (P<0.05) values for ASAT (84.75 iu/L) and ALAT (56.25 %), while T2 (12.50 ml/L) had the highest (P<0.05) values for cholesterol (4.65 mmol/L), urea (8.83 mmol/L), chloride (103.00 mmol/L), bicarbonate (31.50 mmol/L) and sodium (144.75 mmol/L). In conclusion, Mahogany (Khaya senegalensis) bark aqueous extract could be administered at 37.50 ml/L without adverse effect on the blood profile of broiler chickens in the semi-arid zone of Nigeria.
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