Serum Biochemical Response of Growing Rabbits Fed Graded Levels of Genetically Modified Cottonseeds Meal
Abstract
A 90-day biosafety study was conducted to evaluate the potential unintended effects of GM cottonseeds consumption on rabbits’ serum biochemical profile. A total of Forty-eight New Zealand white male and female (24 pairs) rabbits averagely weighing 570.50 ± 0.50 g were assigned to dietary treatments containing different levels of GM cotton seeds (i.e. 20% w/w, 30% w/w and 40% w/w respectively) mixed with standard diet for 90 days. During the course of the study, the levels of various serum enzymes, electrolytes, glucose and serum total cholesterol were measured. The results revealed non-significant (P>0.05) dose-dependent effects in almost all the evaluated parameters except for the serum total cholesterol in which significant differences (P<0.05) were observed. However, such differences were not biologically significant, as all the values were within the reported normal physiological range. The Outcomes from this feeding study demonstrated that the consumption of GM cottonseeds based diets could adversely affect the biochemical profile of rabbits. It is therefore concluded that, the GM cottonseed meal is as safe and nutritious as conventional feed ingredients used in rabbits feeding.
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